Plasticity-Related Gene 1 Affects Mouse Barrel Cortex Function via Strengthening of Glutamatergic Thalamocortical Transmission

Plasticity-related gene-1 (PRG-1) is a brain-specific protein that modulates glutamatergic synaptic transmission. Here we investigated the functional role of PRG-1 in adolescent and adult mouse barrel cortex both in vitro and in vivo. Compared with wild-type (WT) animals, PRG-1-deficient (KO) mice s...

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Udgivet i:Cereb Cortex
Main Authors: Unichenko, Petr, Kirischuk, Sergei, Yang, Jenq-Wei, Baumgart, Jan, Roskoden, Thomas, Schneider, Patrick, Sommer, Angela, Horta, Guilherme, Radyushkin, Konstantin, Nitsch, Robert, Vogt, Johannes, Luhmann, Heiko J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898676/
https://ncbi.nlm.nih.gov/pubmed/26980613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhw066
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