Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats

BACKGROUND: Apolipoprotein E-deficient (ApoE(−/−)) rodents spontaneously develop severe hypercholesterolemia and increased aortic stiffness, both accepted risk factors for cardiovascular morbidity and mortality in humans. In patients with resistant hypertension renal denervation (RDN) may improve ar...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Hohl, Mathias, Linz, Dominik, Fries, Peter, Müller, Andreas, Stroeder, Jonas, Urban, Daniel, Speer, Thimoteus, Geisel, Jürgen, Hummel, Björn, Laufs, Ulrich, Schirmer, Stephan H., Böhm, Michael, Mahfoud, Felix
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898354/
https://ncbi.nlm.nih.gov/pubmed/27277003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0914-9
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