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Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats

BACKGROUND: Apolipoprotein E-deficient (ApoE(−/−)) rodents spontaneously develop severe hypercholesterolemia and increased aortic stiffness, both accepted risk factors for cardiovascular morbidity and mortality in humans. In patients with resistant hypertension renal denervation (RDN) may improve ar...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Hohl, Mathias, Linz, Dominik, Fries, Peter, Müller, Andreas, Stroeder, Jonas, Urban, Daniel, Speer, Thimoteus, Geisel, Jürgen, Hummel, Björn, Laufs, Ulrich, Schirmer, Stephan H., Böhm, Michael, Mahfoud, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898354/
https://ncbi.nlm.nih.gov/pubmed/27277003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0914-9
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