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Structure Determination of the Nuclear Pore Complex with Three-Dimensional Cryo electron Microscopy

Determining the structure of the nuclear pore complex (NPC) imposes an enormous challenge due to its size, intricate composition and membrane-embedded nature. In vertebrates, about 1000 protein building blocks assemble into a 110-MDa complex that fuses the inner and outer membranes of a cell's...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Main Authors: von Appen, Alexander, Beck, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898182/
https://ncbi.nlm.nih.gov/pubmed/26791760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.01.004
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