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Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non–small cell lung cancer cells

BACKGROUND: Radiotherapy is one of the main therapeutic approaches for non–small cell lung cancer (NSCLC). However, radioresistant cancer cells can eventually cause tumor relapse and even fatal metastasis. It is thought that radioresistance and metastasis could be potentially linked by epithelial-me...

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Bibliografske podrobnosti
izdano v:Chin J Cancer
Main Authors: Yao, Yuan-Hu, Cui, Yan, Qiu, Xiang-Nan, Zhang, Long-Zhen, Zhang, Wei, Li, Hao, Yu, Jin-Ming
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897817/
https://ncbi.nlm.nih.gov/pubmed/27266881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0113-3
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