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A method to estimate the contribution of regional genetic associations to complex traits from summary association statistics
Despite considerable efforts, known genetic associations only explain a small fraction of predicted heritability. Regional associations combine information from multiple contiguous genetic variants and can improve variance explained at established association loci. However, regional associations are...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4897708/ https://ncbi.nlm.nih.gov/pubmed/27273519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27644 |
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