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Reduced cerebral cortical but elevated striatal concentration of somatostatin-like immunoreactivity in dominantly inherited olivopontocerebellar atrophy.

Somatostatin-like immunoreactivity (SLI) was measured in the brains of nine patients with dominantly inherited olivopontocerebellar atrophy (OPCA), who all had a marked deficit of the cholinergic marker choline-acetyltransferase (ChAT) in the cerebral cortex and striatum. Mean concentrations of SLI...

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Bibliographic Details
Main Authors: Kish, S J, Robitaille, Y, el-Awar, M, Schut, L, DiStefano, L, Ball, M J, Mazurek, M F
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC489740/
https://ncbi.nlm.nih.gov/pubmed/8105030
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