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Development and Validation of an Affinity Chromatography-Protein G Method for IgG Quantification

Nimotuzumab, an IgG that recognizes the epidermal growth factor receptor (EGF-R) overexpressed in some tumors, is used in the treatment of advanced head and neck cancer. For the quantification of this protein in cell culture supernatants, protein G-HPLC affinity chromatography is used due to its hig...

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Publicat a:Int Sch Res Notices
Autors principals: Paradina Fernández, Lesly, Calvo, Loany, Viña, Lisel
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897240/
https://ncbi.nlm.nih.gov/pubmed/27379284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/487101
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