Peptidylarginine Deiminase Inhibitor Suppresses Neutrophil Extracellular Trap Formation and MPO-ANCA Production

Myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis is a systemic small-vessel vasculitis, wherein, MPO-ANCA plays a critical role in the pathogenesis. Neutrophil extracellular traps (NETs) released from activated neutrophils are composed of extracellular web-like DN...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kusunoki, Yoshihiro, Nakazawa, Daigo, Shida, Haruki, Hattanda, Fumihiko, Miyoshi, Arina, Masuda, Sakiko, Nishio, Saori, Tomaru, Utano, Atsumi, Tatsuya, Ishizu, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896908/
https://ncbi.nlm.nih.gov/pubmed/27375623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00227
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