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Human neutrophil peptides upregulate expression of cyclooxygenase-2 and endothelin-1 by inducing oxidative stress
The human neutrophil peptides (HNP) bind to vascular smooth muscle cells and regulate vascular tone. We hypothesized that HNP act on endothelial cells to modulate the expression of vasoactive byproducts. We observed a time- and dose-dependent increase in the expression of cyclooxygenase-2 (COX-2) by...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896815/ https://ncbi.nlm.nih.gov/pubmed/18441204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00211.2008 |
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