Resistance to docetaxel in prostate cancer is associated with androgen receptor activation and loss of KDM5D expression

The androgen receptor (AR) plays an essential role in prostate cancer, and suppression of its signaling with androgen deprivation therapy (ADT) has been the mainstay of treatment for metastatic hormone-sensitive prostate cancer for more than 70 y. Chemotherapy has been reserved for metastatic castra...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Komura, Kazumasa, Jeong, Seong Ho, Hinohara, Kunihiko, Qu, Fangfang, Wang, Xiaodong, Hiraki, Masayuki, Azuma, Haruhito, Lee, Gwo-Shu Mary, Kantoff, Philip W., Sweeney, Christopher J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896695/
https://ncbi.nlm.nih.gov/pubmed/27185910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600420113
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы