Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model

BACKGROUND: Glioblastomas are highly vascularized tumors with a prominent infiltration of macrophages/microglia whose role in promoting glioma growth, invasion, and angiogenesis has not been fully elucidated. METHODS: The contribution of myeloid-derived vascular endothelial growth factor (VEGF) to g...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Osterberg, Nadja, Ferrara, Napoleone, Vacher, Jean, Gaedicke, Simone, Niedermann, Gabriele, Weyerbrock, Astrid, Doostkam, Soroush, Schaefer, Hans-Eckart, Plate, Karl H., Machein, Marcia Regina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896547/
https://ncbi.nlm.nih.gov/pubmed/26951383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now005
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