Transposable elements and their KRAB-ZFP controllers regulate gene expression in adult tissues

KRAB-containing zinc finger proteins (KRAB-ZFPs) are early embryonic controllers of transposable elements (TEs), which they repress with their cofactor KAP1 through histone and DNA methylation, a process thought to result in irreversible silencing. Using a target-centered functional screen, we match...

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Publicado no:Dev Cell
Main Authors: Ecco, Gabriela, Cassano, Marco, Kauzlaric, Annamaria, Duc, Julien, Coluccio, Andrea, Offner, Sandra, Imbeault, Michaël, Rowe, Helen M., Turelli, Priscilla, Trono, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896391/
https://ncbi.nlm.nih.gov/pubmed/27003935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.02.024
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