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Tumour Suppressor Adenomatous Polyposis Coli (APC) localisation is regulated by both Kinesin-1 and Kinesin-2

Microtubules and their associated proteins (MAPs) underpin the polarity of specialised cells. Adenomatous polyposis coli (APC) is one such MAP with a multifunctional agenda that requires precise intracellular localisations. Although APC has been found to associate with kinesin-2 subfamily members, t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ruane, Peter T., Gumy, Laura F., Bola, Becky, Anderson, Beverley, Wozniak, Marcin J., Hoogenraad, Casper C., Allan, Victoria J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895226/
https://ncbi.nlm.nih.gov/pubmed/27272132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27456
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