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The morphogen Decapentaplegic employs a two-tier mechanism to activate target retinal determining genes during ectopic eye formation in Drosophila

Understanding the role of morphogen in activating its target genes, otherwise epigenetically repressed, during change in cell fate specification is a very fascinating yet relatively unexplored domain. Our in vivo loss-of-function genetic analyses reveal that specifically during ectopic eye formation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aggarwal, Poonam, Gera, Jayati, Mandal, Lolitika, Mandal, Sudip
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895176/
https://ncbi.nlm.nih.gov/pubmed/27270790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27270
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