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The morphogen Decapentaplegic employs a two-tier mechanism to activate target retinal determining genes during ectopic eye formation in Drosophila

Understanding the role of morphogen in activating its target genes, otherwise epigenetically repressed, during change in cell fate specification is a very fascinating yet relatively unexplored domain. Our in vivo loss-of-function genetic analyses reveal that specifically during ectopic eye formation...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Aggarwal, Poonam, Gera, Jayati, Mandal, Lolitika, Mandal, Sudip
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895176/
https://ncbi.nlm.nih.gov/pubmed/27270790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27270
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