Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis

In humans, low-energy diets rapidly reduce hepatic fat and improve/normalise glycemic control. Due to difficulties in obtaining human liver, little is known about changes to the lipid species and pathway fluxes that occur under these conditions. Using a combination of stable isotope, and targeted me...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Kowalski, Greg M., Hamley, Steven, Selathurai, Ahrathy, Kloehn, Joachim, De Souza, David P., O’Callaghan, Sean, Nijagal, Brunda, Tull, Dedreia L., McConville, Malcolm J., Bruce, Clinton R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895138/
https://ncbi.nlm.nih.gov/pubmed/27273128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27541
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