Ubiquitin-Like Proteasome System Represents a Eukaryotic-Like Pathway for Targeted Proteolysis in Archaea

The molecular mechanisms of targeted proteolysis in archaea are poorly understood, yet they may have deep evolutionary roots shared with the ubiquitin-proteasome system of eukaryotic cells. Here, we demonstrate in archaea that TBP2, a TATA-binding protein (TBP) modified by ubiquitin-like isopeptide...

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Udgivet i:mBio
Main Authors: Fu, Xian, Liu, Rui, Sanchez, Iona, Silva-Sanchez, Cecilia, Hepowit, Nathaniel L., Cao, Shiyun, Chen, Sixue, Maupin-Furlow, Julie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895103/
https://ncbi.nlm.nih.gov/pubmed/27190215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00379-16
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