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The well-accepted notion that gene amplification contributes to increased expression still remains, after all these years, a reasonable but unproven assumption
“Gene amplification causes overexpression” is a longstanding and well-accepted concept in cancer genetics. However, raking the whole literature, we find only statistical analyses showing a positive correlation between gene copy number and expression level, but do not find convincing experimental cor...
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| Veröffentlicht in: | J Carcinog |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Medknow Publications & Media Pvt Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4895059/ https://ncbi.nlm.nih.gov/pubmed/27298590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.182809 |
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