CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

White adipose tissue (WAT) overgrowth in obesity is linked with increased aggressiveness of certain cancers. Adipose stromal cells (ASCs) can become mobilized from WAT, recruited by tumours and promote cancer progression. Mechanisms underlying ASC trafficking are unclear. Here we demonstrate that ch...

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Vydáno v:Nat Commun
Hlavní autoři: Zhang, Tao, Tseng, Chieh, Zhang, Yan, Sirin, Olga, Corn, Paul G., Li-Ning-Tapia, Elsa M., Troncoso, Patricia, Davis, John, Pettaway, Curtis, Ward, John, Frazier, Marsha L., Logothetis, Christopher, Kolonin, Mikhail G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895055/
https://ncbi.nlm.nih.gov/pubmed/27241286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11674
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