Subtype C gp140 Vaccine Boosts Immune Responses Primed by the South African AIDS Vaccine Initiative DNA-C2 and MVA-C HIV Vaccines after More than a 2-Year Gap

A phase I safety and immunogenicity study investigated South African AIDS Vaccine Initiative (SAAVI) HIV-1 subtype C (HIV-1C) DNA vaccine encoding Gag-RT-Tat-Nef and gp150, boosted with modified vaccinia Ankara (MVA) expressing matched antigens. Following the finding of partial protective efficacy i...

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Dettagli Bibliografici
Pubblicato in:Clin Vaccine Immunol
Autori principali: Gray, Glenda E., Mayer, Kenneth H., Elizaga, Marnie L., Bekker, Linda-Gail, Allen, Mary, Morris, Lynn, Montefiori, David, De Rosa, Stephen C., Sato, Alicia, Gu, Niya, Tomaras, Georgia D., Tucker, Timothy, Barnett, Susan W., Mkhize, Nonhlanhla N., Shen, Xiaoying, Downing, Katrina, Williamson, Carolyn, Pensiero, Michael, Corey, Lawrence, Williamson, Anna-Lise
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895009/
https://ncbi.nlm.nih.gov/pubmed/27098021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00717-15
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