Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Fever is a universal response to infection, and opportunistic pathogens such as Candida albicans have evolved complex circuitry to sense and respond to heat. Here we harness RNA-seq and ChIP-seq to discover that the heat shock transcription factor, Hsf1, binds distinct motifs in nucleosome-depleted...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Leach, Michelle D., Farrer, Rhys A., Tan, Kaeling, Miao, Zhengqiang, Walker, Louise A., Cuomo, Christina A., Wheeler, Robert T., Brown, Alistair J. P., Wong, Koon Ho, Cowen, Leah E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894976/
https://ncbi.nlm.nih.gov/pubmed/27226156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11704
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk