Molecular evidence of functional progesterone withdrawal in human myometrium

Progesterone suppresses uterine contractility acting through its receptors (PRA/B). The mechanism by which human labour is initiated in the presence of elevated circulating progesterone has remained an enigma since Csapo first theorized of a functional withdrawal of progesterone in 1965. Here we rep...

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Udgivet i:Nat Commun
Main Authors: Nadeem, Lubna, Shynlova, Oksana, Matysiak-Zablocki, Elzbieta, Mesiano, Sam, Dong, Xuesen, Lye, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894948/
https://ncbi.nlm.nih.gov/pubmed/27220952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11565
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