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β(3) Integrin Promotes Long-Lasting Activation and Polarization of Vascular Endothelial Growth Factor Receptor 2 by Immobilized Ligand

OBJECTIVE—: During neovessel formation, angiogenic growth factors associate with the extracellular matrix. These immobilized factors represent a persistent stimulus for the otherwise quiescent endothelial cells (ECs), driving directional EC migration and proliferation and leading to new blood vessel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Ravelli, Cosetta, Grillo, Elisabetta, Corsini, Michela, Coltrini, Daniela, Presta, Marco, Mitola, Stefania
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894810/
https://ncbi.nlm.nih.gov/pubmed/26293466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306230
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