A Randomized, Double-Blind, Double-Dummy Study to Evaluate the Intranasal Human Abuse Potential and Pharmacokinetics of a Novel Extended-Release Abuse-Deterrent Formulation of Oxycodone

Objective. Evaluate the human abuse potential (HAP) of an experimental, microsphere-in-capsule formulation of extended-release oxycodone (oxycodone DETERx®) (herein “DETERx”). Design. Randomized, double-blind, double-dummy, positive- and placebo-controlled, single-dose, four-phase, four-treatment, c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pain Med
Prif Awduron: Webster, Lynn R., Kopecky, Ernest A., Smith, Michael D., Fleming, Alison B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
OPIOIDS, SUBSTANCE ABUSE & ADDICTIONS SECTION
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894244/
https://ncbi.nlm.nih.gov/pubmed/26814256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pm/pnv020
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