Apolipoprotein AI Deficiency Inhibits Serum Opacity Factor Activity against Plasma High Density Lipoprotein via a Stabilization Mechanism

The reaction of Streptococcal serum opacity factor (SOF) against plasma high-density lipoproteins (HDL) produces a large cholesteryl ester-rich microemulsion (CERM), a smaller neo HDL that is apolipoprotein (apo) AI-poor, and lipid-free apo AI. SOF is active vs. both human and mouse plasma HDL. In v...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Rosales, Corina, Patel, Niket, Gillard, Baiba K., Yelamanchili, Dedipya, Yang, Yaliu, Courtney, Harry S., Santos, Raul D., Gotto, Antonio M., Pownall, Henry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893950/
https://ncbi.nlm.nih.gov/pubmed/25790332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501486z
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