Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker Trimethylamine N-oxide from dietary precursors

The etiology of cardiovascular disease (CVD) is impacted by multiple modifiable and non-modifiable risk factors including dietary choices, genetic predisposition, and environmental exposures. However, mechanisms linking diet, exposure to pollutants, and CVD risk are largely unclear. Recent studies i...

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Detalhes bibliográficos
Publicado no:J Nutr Biochem
Main Authors: Petriello, Michael C, Hoffman, Jessie B, Sunkara, Manjula, Wahlang, Banrida, Perkins, Jordan T, Morris, Andrew J, Hennig, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893916/
https://ncbi.nlm.nih.gov/pubmed/27155921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2016.03.016
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