High tau levels in cerebrospinal fluid predict nursing home placement and rapid progression in Alzheimer’s disease

BACKGROUND: Increased concentrations of cerebrospinal fluid (CSF) total tau (t-tau) and phosphorylated tau, as well as decreased amyloid-β 42 peptide, are biomarkers of Alzheimer’s disease (AD) pathology, but few studies have shown an association with AD progression rate. We hypothesized that high C...

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Bibliografiske detaljer
Udgivet i:Alzheimers Res Ther
Main Authors: Degerman Gunnarsson, Malin, Ingelsson, Martin, Blennow, Kaj, Basun, Hans, Lannfelt, Lars, Kilander, Lena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893835/
https://ncbi.nlm.nih.gov/pubmed/27263933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-016-0191-0
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