NADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma

BACKGROUND: Bronchial epithelial ciliary dysfunction is an important feature of asthma. We sought to determine the role in asthma of neutrophilic inflammation and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in ciliary dysfunction. METHODS: Bronchial epithelial ciliary function was a...

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Detalhes bibliográficos
Publicado no:Chest
Main Authors: Wan, Wing-Yan Heidi, Hollins, Fay, Haste, Louise, Woodman, Lucy, Hirst, Robert A., Bolton, Sarah, Gomez, Edith, Sutcliffe, Amanda, Desai, Dhananjay, Chachi, Latifa, Mistry, Vijay, Szyndralewiez, Cédric, Wardlaw, Andrew, Saunders, Ruth, O’Callaghan, Christopher, Andrew, Peter W., Brightling, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2016
Assuntos:
Original Research: Asthma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893823/
https://ncbi.nlm.nih.gov/pubmed/26836936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chest.2016.01.024
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