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Genetic basis of common human disease: Insight into the role of Missense SNPs from Genome Wide Association Studies

Recent genome wide association studies have led to the reliable identification of SNPs at a number of loci associated with increased risk of specific common human diseases. Each such locus implicates multiple possible candidate SNPs for involvement in disease mechanism. A variety of mechanisms may l...

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Publicat a:J Mol Biol
Autors principals: Pal, Lipika R., Moult, John
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893807/
https://ncbi.nlm.nih.gov/pubmed/25937569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.04.014
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