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Modeling the interactions of bacteria and Toll-like receptor-mediated inflammation in necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a severe disease of the gastrointestinal tract in premature infants, characterized by a disrupted intestinal epithelium and an exaggerated pro-inflammatory response. Since the activation of Toll-like receptor-4 (TLR4) blocks cell migration and proliferation and con...

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Dades bibliogràfiques
Publicat a:J Theor Biol
Autors principals: Arciero, Julia, Ermentrout, G. Bard, Siggers, Richard, Afrazi, Amin, Hackam, David, Vodovotz, Yoram, Rubin, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893796/
https://ncbi.nlm.nih.gov/pubmed/23238281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.12.002
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