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Chromatin Scanning by Dynamic Binding of Pioneer Factors

Pioneer factors such as FoxA target nucleosomal DNA and initiate cooperative interactions at silent genes during development, cellular reprogramming, and steroid hormone induction. Biophysical studies previously showed that the nuclear mobility of FoxA1 is slower than many other transcription factor...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Zaret, Kenneth S., Lerner, Jonathan, Iwafuchi-Doi, Makiko
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893772/
https://ncbi.nlm.nih.gov/pubmed/27259199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.024
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