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Polymer-DNA Nanoparticle-Induced CXCR4 Overexpression Improves Stem Cell Engraftment and Tissue Regeneration in a Mouse Hindlimb Ischemia Model

Peripheral arterial disease affects nearly 202 million individuals worldwide, sometimes leading to non-healing ulcers or limb amputations in severe cases. Genetically modified stem cells offer potential advantages for therapeutically inducing angiogenesis via augmented paracrine release mechanisms a...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Deveza, Lorenzo, Choi, Jeffrey, Lee, Jerry, Huang, Ngan, Cooke, John, Yang, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893644/
https://ncbi.nlm.nih.gov/pubmed/27279910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.12866
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