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Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres

Structural centrosome aberrations are frequently observed in early stage carcinomas, but their role in malignant transformation is poorly understood. Here, we examined the impact of overexpression of Ninein-like protein (Nlp) on the architecture of polarized epithelia in three-dimensional mammospher...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Schnerch, D, Nigg, E A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893635/
https://ncbi.nlm.nih.gov/pubmed/26364601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.332
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