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Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo

Non-coding RNAs provide additional regulatory layers to gene expression as well as the potential to being exploited as therapeutic tools. Non-coding RNA-based therapeutic approaches have been attempted in dominant diseases, however their use for treatment of genetic diseases caused by insufficient g...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Indrieri, Alessia, Grimaldi, Claudia, Zucchelli, Silvia, Tammaro, Roberta, Gustincich, Stefano, Franco, Brunella
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893607/
https://ncbi.nlm.nih.gov/pubmed/27265476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27315
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