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Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo

Non-coding RNAs provide additional regulatory layers to gene expression as well as the potential to being exploited as therapeutic tools. Non-coding RNA-based therapeutic approaches have been attempted in dominant diseases, however their use for treatment of genetic diseases caused by insufficient g...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Indrieri, Alessia, Grimaldi, Claudia, Zucchelli, Silvia, Tammaro, Roberta, Gustincich, Stefano, Franco, Brunella
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893607/
https://ncbi.nlm.nih.gov/pubmed/27265476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27315
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