RNF8 promotes epithelial-mesenchymal transition of breast cancer cells

BACKGROUND: Epithelial-mesenchymal transition (EMT) is a crucial step for solid tumor progression and plays an important role in cancer invasion and metastasis. RNF8 is an ubiquitin E3 ligase with RING domain, and plays essential roles in DNA damage response and cell cycle regulation. However the ro...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Kuang, Jingyu, Li, Li, Guo, Limei, Su, Yanrong, Wang, Yuxuan, Xu, Yongjie, Wang, Xiaozhen, Meng, Shucong, Lei, Liandi, Xu, Luzheng, Shao, Genze
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893263/
https://ncbi.nlm.nih.gov/pubmed/27259701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0363-6
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