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RNF8 promotes epithelial-mesenchymal transition of breast cancer cells
BACKGROUND: Epithelial-mesenchymal transition (EMT) is a crucial step for solid tumor progression and plays an important role in cancer invasion and metastasis. RNF8 is an ubiquitin E3 ligase with RING domain, and plays essential roles in DNA damage response and cell cycle regulation. However the ro...
Enregistré dans:
Publié dans: | J Exp Clin Cancer Res |
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Auteurs principaux: | , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893263/ https://ncbi.nlm.nih.gov/pubmed/27259701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0363-6 |
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