Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation

BACKGROUND: Histamine is an amine widely known as a peripheral inflammatory mediator and as a neurotransmitter in the central nervous system. Recently, it has been suggested that histamine acts as an innate modulator of microglial activity. Herein, we aimed to disclose the role of histamine in micro...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Rocha, Sandra M., Saraiva, Tatiana, Cristóvão, Ana C., Ferreira, Raquel, Santos, Tiago, Esteves, Marta, Saraiva, Cláudia, Je, Goun, Cortes, Luísa, Valero, Jorge, Alves, Gilberto, Klibanov, Alexander, Kim, Yoon-Seong, Bernardino, Liliana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893260/
https://ncbi.nlm.nih.gov/pubmed/27260166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0600-0
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