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A live attenuated Salmonella Enteritidis secreting detoxified heat labile toxin enhances mucosal immunity and confers protection against wild-type challenge in chickens

A live attenuated Salmonella Enteritidis (SE) capable of constitutively secreting detoxified double mutant Escherichia coli heat labile toxin (dmLT) was developed. The biologically adjuvanted strain was generated via transformation of a highly immunogenic SE JOL1087 with a plasmid encoding dmLT gene...

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Bibliografiska uppgifter
I publikationen:Vet Res
Huvudupphovsmän: Lalsiamthara, Jonathan, Kamble, Nitin Machindra, Lee, John Hwa
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893257/
https://ncbi.nlm.nih.gov/pubmed/27262338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-016-0348-7
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