Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study

OBJECTIVE: To assess the effect of sildenafil, a phosphodiesterase type 5 inhibitor, on digital ulcer (DU) healing in systemic sclerosis (SSc). METHODS: Randomised, placebo-controlled study in patients with SSc to assess the effect of sildenafil 20 mg or placebo, three times daily for 12 weeks, on i...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Hachulla, Eric, Hatron, Pierre-Yves, Carpentier, Patrick, Agard, Christian, Chatelus, Emmanuel, Jego, Patrick, Mouthon, Luc, Queyrel, Viviane, Fauchais, Anne-Laure, Michon-Pasturel, Ulrique, Jaussaud, Roland, Mathian, Alexis, Granel, Brigitte, Diot, Elisabeth, Farge-Bancel, Dominique, Mekinian, Arsène, Avouac, Jérôme, Desmurs-Clavel, Hélène, Clerson, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893100/
https://ncbi.nlm.nih.gov/pubmed/25995322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-207001
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