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Sleep drive is encoded by neural plastic changes in a dedicated circuit

Prolonged wakefulness leads to an increased pressure for sleep, but how this homeostatic drive is generated and subsequently persists is unclear. Here, from a neural circuit screen in Drosophila, we identify a subset of ellipsoid body (EB) neurons whose activation generates sleep drive. Patch-clamp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Liu, Sha, Liu, Qili, Tabuchi, Masashi, Wu, Mark N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892967/
https://ncbi.nlm.nih.gov/pubmed/27212237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.013
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