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High-level expression and preparation of recombinant human fibrinogen as biopharmaceuticals
Fibrinogen is a large and complex glycoprotein containing two sets of each of three different chains (α, β and γ). There have been no reports of high-level expression of fibrinogen at commercial levels using mammalian cultured cells such as CHO cells because of the difficulty in highly expressing a...
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| Publicado no: | J Biochem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892781/ https://ncbi.nlm.nih.gov/pubmed/26475674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv099 |
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