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The Central Cavity of ABCB1 Undergoes Alternating Access During ATP Hydrolysis
Understanding the process that underlies multi-drug recognition and efflux by P-glycoprotein (ABCB1) remains a key biological challenge. Structural data has recently become available for the murine and C. elegans homologues of ABCB1; however all structures were obtained in the absence of nucleotide....
में बचाया:
| में प्रकाशित: | FEBS J |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892341/ https://ncbi.nlm.nih.gov/pubmed/24597976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12773 |
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