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The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen.

Immunoglobulin G fractions from patients with Lambert-Eaton myasthenic syndrome (LEMS), an autoimmune disease of neuromuscular transmission, immunoprecipitate 125I-labeled omega-conotoxin GVIA-labeled calcium channels solubilized from rat brain. A 58-kDa antigen was detected by probing Western blots...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Leveque, C, Hoshino, T, David, P, Shoji-Kasai, Y, Leys, K, Omori, A, Lang, B, el Far, O, Sato, K, Martin-Moutot, N
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3625
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