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Intrathecal T‐cell clonal expansions in patients with multiple sclerosis

OBJECTIVE: Analysis of the T‐cell receptor (TCR) repertoire in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) can reveal antigen‐specific immune responses potentially implicated in the disease process. We applied a new unbiased deep‐sequencing method for TCR repertoire analys...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: de Paula Alves Sousa, Alessandra, Johnson, Kory R., Nicholas, Richard, Darko, Sam, Price, David A., Douek, Daniel C., Jacobson, Steven, Muraro, Paolo A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891996/
https://ncbi.nlm.nih.gov/pubmed/27547770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.310
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