Eastern Cooperative Oncology Group (E1201) randomized phase II trial of neoadjuvant preoperative paclitaxel/cisplatin/radiotherapy (RT) or irinotecan/cisplatin/RT in esophageal adenocarcinoma: long term outcome and implications for trial design

BACKGROUND: Toxicity, pathologic CR, and long term outcomes are reported for the neoadjuvant therapies assessed in a randomized phase II trial for operable esophageal adenocarcinoma, staged II-IVa by endoscopy/ultrasound (EUS). METHODS: 86 eligible patients (pts) began treatment. Arm A preoperative...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Kleinberg, Lawrence R., Catalano, Paul, Forastiere, Arlene A., Keller, Steven M., Mitchel, Edith P., Anne, Pramila Rani, Benson, Al B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891943/
https://ncbi.nlm.nih.gov/pubmed/26972646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2015.12.009
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