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TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis

Previous study showed that TIGAR (TP53-induced glycolysis and apoptosis regulator) protected ischemic brain injury via enhancing pentose phosphate pathway (PPP) flux and preserving mitochondria function. This study was aimed to study the role of TIGAR in cerebral preconditioning. The ischemic precon...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Zhou, Jun-Hao, Zhang, Tong-Tong, Song, Dan-Dan, Xia, Yun-Fei, Qin, Zheng-Hong, Sheng, Rui
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891774/
https://ncbi.nlm.nih.gov/pubmed/27256465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27096
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