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Non-random distribution of homo-repeats: links with biological functions and human diseases

The biological function of multiple repetitions of single amino acids, or homo-repeats, is largely unknown, but their occurrence in proteins has been associated with more than 20 hereditary diseases. Analysing 122 bacterial and eukaryotic genomes, we observed that the number of proteins containing h...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lobanov, Michail Yu., Klus, Petr, Sokolovsky, Igor V., Tartaglia, Gian Gaetano, Galzitskaya, Oxana V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891720/
https://ncbi.nlm.nih.gov/pubmed/27256590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26941
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