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Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

The tetra-branched peptide NT4 selectively binds to different human cancer cells and tissues. NT4 specifically binds to sulfated glycosaminoglycans on cancer cell membranes. Since sulfated glycosaminoglycans are involved in cancer cell interaction with the extracellular matrix, we evaluated the effe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Brunetti, Jlenia, Depau, Lorenzo, Falciani, Chiara, Gentile, Mariangela, Mandarini, Elisabetta, Riolo, Giulia, Lupetti, Pietro, Pini, Alessandro, Bracci, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891694/
https://ncbi.nlm.nih.gov/pubmed/27255651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27174
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