HMGB1 exacerbates bronchiolitis obliterans syndrome via RAGE/NF-κB/HPSE signaling to enhance latent TGF-β release from ECM

Bronchiolitis obliterans syndrome (BOS), characterized by progressive airflow obstruction, is the main barrier to long-term graft survival after lung transplantation. Despite extensive studies, the mechanisms underlying BOS remain poorly understood, and targeted interventions have not yet been fully...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: He, Long, Sun, Fei, Wang, Yi, Zhu, Jianghui, Fang, Jing, Zhang, Shu, Yu, Qilin, Gong, Quan, Ren, Boxue, Xiang, Xudong, Chen, Zhishui, Ning, Qin, Hu, Jifa, Yang, Ping, Wang, Cong-Yi
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891412/
https://ncbi.nlm.nih.gov/pubmed/27347307
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