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miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2
MicroRNA array analysis revealed that miR-217 expression was decreased in anti-cancer drug-resistant Malme3M(R) cancer cells. CAGE, a cancer/testis antigen, was predicted as a target of miR-217. Luciferase activity and ChIP assays revealed a negative feedback relationship between CAGE and miR-217. m...
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| Yayımlandı: | Oncotarget |
|---|---|
| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891121/ https://ncbi.nlm.nih.gov/pubmed/26863629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7185 |
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