Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

Spliceosome mutations are frequently observed in patients with myelodysplastic syndromes (MDS). However, it is largely unknown how these mutations contribute to the disease. MicroRNAs (miRNAs) are small noncoding RNAs, which have been implicated in most human cancers due to their role in post transc...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Aslan, Derya, Garde, Christian, Nygaard, Mette Katrine, Helbo, Alexandra Søgaard, Dimopoulos, Konstantinos, Hansen, Jakob Werner, Severinsen, Marianne Tang, Treppendahl, Marianne Bach, Sjø, Lene Dissing, Grønbæk, Kirsten, Kristensen, Lasse Sommer
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891095/
https://ncbi.nlm.nih.gov/pubmed/26848861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7127
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