Depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation

Our previous study revealed that knockdown of CABYR-a/b increases the chemosensitivity of lung cancer cells through inactivation of Akt. Here, we demonstrated that depletion of CABYR-a/b significantly increased DR5 expression and sensitized lung cancer cells to TRAIL-induced apoptosis in vitro and/o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xiao, Qianqian, Qian, Zunlei, Zhang, Weiqing, Liu, Jin, Hu, Enze, Zhang, Jinsan, Li, Mingying, Wang, Junhao, Kong, Fei, Li, Yunguang, Wang, Rui, Tan, Xiaohua, He, Dacheng, Xiao, Xueyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891056/
https://ncbi.nlm.nih.gov/pubmed/26843620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7069
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